Alkermes的环境保护和可持续性方法金博宝怎么注册

环境al Protection and Sustainability

We strive to conduct our business activities in a manner that minimizes the environmental impacts of our operations and promotes effective stewardship of environmental resources. We are committed to complying with applicable laws, rules and regulations and operating with the highest standards of conduct. All Alkermes facilities are subject to routine regulatory inspections in respect to EHSS to confirm compliance with applicable laws and regulations.

我们努力在整个组织中保持一种可持续性文化，并在内部利益相关者群体和职能金博宝怎么注册之间进行协作，以确定降低风险，提高运营效率并减少我们的环境影响的方法，包括与资源使用，废物管理和气候变化有关的影响。

在2020年，我们聘请了一个独立的第三方，对我们运营职能的领导者进行重点调查，包括我们的研发，制造业，质量，外部运营和供应链，EHSS和工程团队的代表，以确定确定环境重点领域对我们的业务运营的最高重要性。根据本调查的结果，我们确定了以下关键环境重点领域：

• 能源使用，温室气体排放和可再生能源
• Waste Optimization
• Pharmaceuticals in the Environment
• Water Conservation
• Sustainability in the Supply Network

In 2021, we established a global, cross-functional sustainability steering team to further develop and enhance our focus on these areas.

能源使用

We continually monitor and review our energy usage in order to identify opportunities for further optimization and reduction. Our activities in support of this objective include:

• 分析我们设施中电力和天然气监测系统的数据和趋势；
• 用更节能的替代品代替旧设备；
• 将可持续设计和建筑技术纳入新设施，以促进能源使用量更少；和
• Assessments of options to procure and further integrate renewable energy sources into our operations.

A forum of engineering leaders from each of our sites meets regularly to develop best practices for our facilities and utility systems. A sub-team of this group is responsible for integrating sustainability principles and practices into the design of our capital projects, monitoring company-wide energy audits and developing multi-year plans for energy reduction initiatives.

Our overall energy use in 2021 increased by 7% as compared to 2020 in absolute terms. Three key factors contributed to this increase:

• Our new 230,000 square foot, LEED® Silver-certified¹, facility in Waltham, MA was in operation for all of 2021, compared to only eight months of operation in 2020.
• 由于对现场生产的关键产品的vumerity®的需求增加和制造量增加，因此我们阿斯隆的爱尔兰Athlone设施的能源使用增加了。
• Salesforce activity increased as in-person interactions resumed, resulting in, among other impacts, a 29% increase compared to 2020 in fuel usage by our commercial team’s fleet of vehicles.

While these changes were significant, their impact on our overall energy consumption was partially mitigated by ongoing energy efficiency initiatives across our facilities, including energy audits that highlighted opportunities for immediate efficiency improvements, phased capital investments, procedural improvements and behaviorchange initiatives.

温室气排放和可再生能源

Alkermes认识到气候变化造成的严重环境，经济和社会影响。我们的环境可持续性努力包括主动采取行金博宝怎么注册动来减少运营中的温室气体排放。

在2021年，与我们的运营增长相关的绝对能量使用增加，由于上一节中概述的原因，绝对范围1和2温室气体排放量增加了15％。但是，我们的范围范围1和2葡萄质的每$ M收入在2021年减少了3％，比我们2015年的基准年份低43％。碳强度的这种降低强调了我们对减少能源措施的重点以更有效的方式生产我们的药物。

除了关注设施和运营中的能源效率外，我们还鼓励员工在上班时使用更可持续的运输形式，包括通过在我们的沃尔瑟姆，马萨诸塞州和公共交通工具之间提供航天飞机服务，并安装充电站在我们的爱尔兰Athlone设施的电动汽车。

Water Conservation

We recognize that water is a scarce and invaluable resource that we must endeavor to conserve and use efficiently and sustainably. We have implemented programs across our organization to assess, reduce and optimize our water consumption, and we examine opportunities to further conserve water on an ongoing basis. As a result of these efforts, overall absolute source water usage at our facilities decreased 7% in 2021 compared to 2020, and decreased 32% compared to our 2015 baseline measurement year, despite the opening of our new Waltham, MA R&D and office facility. Overall water use per floor space (cubic meters per m2) decreased by 10% compared to 2020 and was 54% lower than our 2015 baseline measurement year.

Pharmaceuticals in the Environment

We understand the significant potential impacts that pharmaceuticals can have on the environment. We maintain strict internal protocols to adhere to the parameters of our applicable licenses and permits, mitigate the impacts of our operations on natural resources such as surface water and groundwater, and assist us in effectively controlling our air and wastewater emissions.

As part of our development and manufacturing scaleup of new, proprietary molecules, we have implemented programs to enable us to understand and mitigate associated environmental impacts. For example, we partner with third-party experts to identify practices to assist us in characterizing and understanding appropriate eco-toxicology and safe discharge limits.

我们已经实施了科学和数据驱动的环境风险缓解策略，并不断评估改善我们的排放控制系统的机会，以更好地保护环境并增强运营的环境可持续性。金博宝怎么注册

Waste Optimization

All Alkermes facilities have comprehensive waste management plans in place and we strive to reduce our generation of waste at each source. Our waste streams are fully segregated, and disposal methods are carefully evaluated to support compliance with statutory and permit requirements and to minimize our environmental impacts.

对于非危害废物，我们积极寻求消除垃圾填埋场，并在可行的情况下进行回收，堆肥和/或其他重复使用机会。我们还采用其他形式的负责处置，例如在第三方“废物到能源”设施中进行治疗。

For hazardous waste, we recognize that landfill is not an environmentally responsible disposal route. We actively explore recycling opportunities for our hazardous waste and, when feasible, select disposal routes that include potential energy recovery benefits.

我们的废物供应商经过精心选择和审查，以促进仅利用负责任的废物处理路线。通过与这些供应商的工作关系，我们能够确定并实施新的机会，以进行负责任的废物处理和进一步减少废料。

Key waste optimization highlights at the enterprise level included:

• 在2021年产生的废物总数中，有92％的回收利用（63％），在废物到能源设施（16％）或焚化（13％）中进行处理（13％）。
• Of total hazardous waste generated in 2021, 96% was either recycled or processed in a waste-to-energy facility and the remainder was incinerated.

我们制造设施的关键废物优化重点包括：

• Wilmington, OH facility: Approximately 98% of hazardous waste was recovered and recycled; the remainder was incinerated.
• 爱尔兰的阿斯隆（Athlone）设施：没有浪费被派往垃圾填埋场；100％的非危害废物和92％的危险废物是在废物到能源设施中进行回收或处理的；其余的被焚化。

¹Leadership in Energy and Environmental Design, developed by the U.S. Green Building Council (USGBC)

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